Acute Erythroid Leukemia - Revision history

Bailey.Glen at 18:45, 12 December 2023

2023-12-12T18:45:12Z

← Older revision		Revision as of 13:45, 12 December 2023
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	==Links==		==Links==

	*[[~~Pure Erythroid Leukemia~~]]		*[[HAEM5:Acute erythroid leukaemia]]

	==References==		==References==

Bailey.Glen at 17:14, 3 November 2023

2023-11-03T17:14:33Z

← Older revision		Revision as of 12:14, 3 November 2023
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	==Notes==		==Notes==
	<nowiki>*</nowiki>Primary authors will typically be those that initially create and complete the content of a page. If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage). Additional global feedback or concerns are also welcome.		<nowiki>*</nowiki>Primary authors will typically be those that initially create and complete the content of a page. If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage). Additional global feedback or concerns are also welcome.

	~~[[Category:Diseases A]]~~

Kilannin.Krysiak: /* Definition / Description of Disease */ typo fix

2022-06-01T16:22:41Z

Definition / Description of Disease: typo fix

← Older revision		Revision as of 11:22, 1 June 2022
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	==Definition / Description of Disease==		==Definition / Description of Disease==

	PEL is a rare form of acute leukemia with an aggressive clinical course and is characterized by an uncontrolled proliferation of immature erythroid precursors (proerythroblastic or undifferentiated) [1-12]. Erythroleukemia (erythroid/myeloid) may be de novo or evolved from myeloid or sometimes from myeloproliferative neoplasms (MPN). [1,10].		PEL is a rare form of acute leukemia with an aggressive clinical course and is characterized by an uncontrolled proliferation of immature erythroid precursors (proerythroblastic or undifferentiated) [1-12]. Erythroleukemia (erythroid/myeloid) may be de novo or evolved from myeloid or sometimes from myeloproliferative neoplasms (MPN) [1,10].

	==Links==		==Links==

	* [[Pure Erythroid Leukemia]]		*[[Pure Erythroid Leukemia]]

	==References==		==References==
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	12. Fauzia SF, et al., (2017). Pure erythroid leukemia: The sole acute erythroid leukemia. Int J Bone Marrow Res 1: 001-05 (open access).		12. Fauzia SF, et al., (2017). Pure erythroid leukemia: The sole acute erythroid leukemia. Int J Bone Marrow Res 1: 001-05 (open access).

	== Notes ==		==Notes==
	<nowiki>*</nowiki>Primary authors will typically be those that initially create and complete the content of a page. If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage). Additional global feedback or concerns are also welcome.		<nowiki>*</nowiki>Primary authors will typically be those that initially create and complete the content of a page. If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage). Additional global feedback or concerns are also welcome.

	[[Category:Diseases A]]		[[Category:Diseases A]]

Jennelleh: /* Cancer Category/Type */

2018-06-10T22:31:35Z

Cancer Category/Type

← Older revision		Revision as of 17:31, 10 June 2018
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	==Cancer Category/Type==		==Cancer Category/Type==

	Acute Myeloid Leukemia		[[AML\|Acute Myeloid Leukemia]]

	==Cancer Sub-Classification / Subtype==		==Cancer Sub-Classification / Subtype==

Jennelleh: /* Links */

2018-05-28T21:37:50Z

Links

← Older revision		Revision as of 16:37, 28 May 2018
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	==Links==		==Links==

	[[Pure Erythroid Leukemia]]		* [[Pure Erythroid Leukemia]]

	==References==		==References==

Jennelleh at 21:21, 28 May 2018

2018-05-28T21:21:06Z

Show changes

Jennelleh: /* Immunophenotype */

2018-05-28T20:46:32Z

Immunophenotype

← Older revision		Revision as of 15:46, 28 May 2018
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	Differentiated PEL may express Glycophorin and hemoglobin A, absence of myeloperoxidase (MPO) and other myeloid markers [1], Blasts are negative for HLA-Dr, CD34, positive for CD117[1]		Differentiated PEL may express Glycophorin and hemoglobin A, absence of myeloperoxidase (MPO) and other myeloid markers [1], Blasts are negative for HLA-Dr, CD34, positive for CD117[1]
	Immature forms can be negative for Glycophorin or weekly expressed. Positive for Carbonic anhydrase 1, Gero antobody against the Gerbich blood group or CD36 especially at earlier stages of differentiation. CD41 and CD61 are negative [1, 12].		Immature forms can be negative for Glycophorin or weekly expressed. Positive for Carbonic anhydrase 1, Gero antobody against the Gerbich blood group or CD36 especially at earlier stages of differentiation. CD41 and CD61 are negative [1, 12].


	{\| class="wikitable sortable"		{\| class="wikitable sortable"

Jennelleh at 20:46, 28 May 2018

2018-05-28T20:46:10Z

← Older revision		Revision as of 15:46, 28 May 2018
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	==Cancer Category/Type==		==Cancer Category/Type==

	~~'''~~Acute Myeloid Leukemia~~'''~~		Acute Myeloid Leukemia

	==Cancer Sub-Classification / Subtype==		==Cancer Sub-Classification / Subtype==
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	==Definition / Description of Disease==		==Definition / Description of Disease==

	~~'''~~In the 2008 WHO classification Acute Erythroid leukemia (AEL) was classified into two subtypes, one subtype was Erythroleukemia and second subtype was pure erythroid leukemia (PEL).		In the 2008 WHO classification Acute Erythroid leukemia (AEL) was classified into two subtypes, one subtype was Erythroleukemia and second subtype was pure erythroid leukemia (PEL). However, in the 2016 WHO update, erythroleukemia was merged into myelodysplastic syndrome, and PEL was described as the only subtype of AEL [1-12]. PEL is a rare form of acute leukemia with an aggressive clinical course and is characterized by an uncontrolled proliferation of immature erythroid precursors (proerythroblastic or undifferentiated) [1-12].
	~~'''~~However, in the 2016 WHO update, erythroleukemia was merged into myelodysplastic syndrome, and PEL was described as the only subtype of AEL [1-12]
	~~'''~~PEL is a rare form of acute leukemia with an aggressive clinical course and is characterized by an uncontrolled proliferation of immature erythroid precursors (proerythroblastic or undifferentiated) [1-12].
	~~''''''~~
	~~'''~~

	==Synonyms / Terminology==		==Synonyms / Terminology==

Jennelleh at 20:45, 28 May 2018

2018-05-28T20:45:31Z

← Older revision		Revision as of 15:45, 28 May 2018
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	==Cancer Sub-Classification / Subtype==		==Cancer Sub-Classification / Subtype==

	~~'''~~Pure Erythroid Leukemia (PEL) is the only subtype in Acute Erythroid Leukemia (AEL).~~'''~~		Pure Erythroid Leukemia (PEL) is the only subtype in Acute Erythroid Leukemia (AEL).

	==Definition / Description of Disease==		==Definition / Description of Disease==

Jennelleh at 20:45, 28 May 2018

2018-05-28T20:45:12Z

← Older revision		Revision as of 15:45, 28 May 2018
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	~~{{Under Construction}}~~
	==Primary Author(s)*==		==Primary Author(s)*==

	Ashwini Yenamandra PhD FACMG		Ashwini Yenamandra PhD FACMG


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