Compendium of Cancer Genome Aberrations

HAEM4:Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN): Difference between revisions

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==General Disease Overview / Description of Cancer Category==
==General Disease Overview / Description of Cancer Category==


The MDS/MPNs include a category of myeloid malignancies with overlapping characteristics of myelodysplastic syndrome ([[Myelodysplastic Syndromes (MDS)|MDS]]) and myeloproliferative neoplasm ([[Myeloproliferative Neoplasms (MPN)|MPN]]) at the time of initial presentation (disease onset).
The MDS/MPNs include a category of myeloid malignancies with overlapping characteristics of myelodysplastic syndrome ([[HAEM4:Myelodysplastic Syndromes (MDS)|MDS]]) and myeloproliferative neoplasm ([[HAEM4:Myeloproliferative Neoplasms (MPN)|MPN]]) at the time of initial presentation (disease onset).


==WHO Classification Pages (Includes Links to Content)==
==WHO Classification Pages (Includes Links to Content)==


*[[Chronic Myelomonocytic Leukemia (CMML)]]
*[[HAEM5:Chronic myelomonocytic leukaemia]]
*[[Atypical Chronic Myeloid Leukemia (aCML), BCR-ABL1 Negative]]
*[[HAEM5:Myelodysplastic/myeloproliferative neoplasm with neutrophilia]]
*[[Juvenile Myelomonocytic Leukemia (JMML)]]
*[[HAEM5:Juvenile myelomonocytic leukaemia]]
*[[Myelodysplastic/Myeloproliferative Neoplasms with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T)|MDS/MPN with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T)]]
*[[HAEM5:Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis|MDS/MPN with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T)]]
*[[Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN), Unclassifiable|MDS/MPN, Unclassifiable]]
*[[HAEM5:Myelodysplastic/myeloproliferative neoplasm, NOS|MDS/MPN, Unclassifiable]]


==Other Related Pages (Includes Links to Content)==
==Other Related Pages (Includes Links to Content)==
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#Previously diagnosed MPN developed cytopenia(s): classification must be based on initial presentation; avoid “reclassification”.
#Previously diagnosed MPN developed cytopenia(s): classification must be based on initial presentation; avoid “reclassification”.
#Cases with well-defined fusions that can be classified otherwise: ''[[Chronic Myeloid Leukemia (CML), BCR-ABL1 Positive|BCR-ABL1]]''; fusion involving ''[[Myeloid/Lymphoid Neoplasms with PDGFRA Rearrangement|PDGFRA]], [[Myeloid/Lymphoid Neoplasms with PDGFRB Rearrangement|PDGFRB]]'', or ''[[Myeloid/Lymphoid Neoplasms with FGFR1 Rearrangement|FGFR1]]''; or ''[[Myeloid/Lymphoid Neoplasms with PCM1-JAK2|PCM1-JAK2]]''.
#Cases with well-defined fusions that can be classified otherwise: ''[[HAEM5:Chronic myeloid leukaemia|BCR-ABL1]]''; fusion involving ''[[HAEM5:Myeloid/lymphoid neoplasm with PDGFRA rearrangement|PDGFRA]], [[HAEM5:Myeloid/lymphoid neoplasm with PDGFRB rearrangement|PDGFRB]]'', or ''[[HAEM5:Myeloid/lymphoid neoplasm with FGFR1 rearrangement|FGFR1]]''; or ''[[HAEM5:Myeloid/lymphoid neoplasm with JAK2 rearrangement|PCM1-JAK2]]''.


==References==
==References==
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