HAEM5:Acute myeloid leukaemia with BCR::ABL1 fusion: Difference between revisions

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{{DISPLAYTITLE:Acute myeloid leukaemia with BCR::ABL1 fusion}}
{{DISPLAYTITLE:Acute myeloid leukaemia with BCR::ABL1 fusion}}
[[HAEM5:Table_of_Contents|Haematolymphoid Tumours (WHO Classification, 5th ed.)]]
[[HAEM5:Table_of_Contents|Haematolymphoid Tumours (WHO Classification, 5th ed.)]]


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==WHO Essential and Desirable Genetic Diagnostic Criteria==
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|WHO Essential Criteria (Genetics)*
|a myeloid neoplasm with >20% blasts expressing a myeloid immunophenotype in the bone marrow and/or peripheral blood; detection of ''BCR::ABL1'' at initial diagnosis; lack of features of chronic myeloid leukaemia (CML) before or at diagnosis or after therapy.
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|WHO Desirable Criteria (Genetics)*
|presence of t(9;22)(q34;q11.2) on conventional karyotyping; determination of the ''BCR::ABL1'' transcript subtype and establishment of a baseline level of ''BCR::ABL1'' transcript subtype and establishment of a baseline level of ''BCR::ABL1'' transcript for monitoring treatment response.
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|Other Classification
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<nowiki>*</nowiki>Note: These are only the genetic/genomic criteria. Additional diagnostic criteria can be found in the [https://tumourclassification.iarc.who.int/home <u>WHO Classification of Tumours</u>].
==Related Terminology==
==Related Terminology==