Compendium of Cancer Genome Aberrations

Tumours of Haematopoietic and Lymphoid Tissues: Difference between revisions

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==Myeloproliferative Neoplasms (MPN) ([[HAEM4:Myeloproliferative Neoplasms (MPN)|Overview Page Link]])==
==Myeloproliferative Neoplasms (MPN) ([[Myeloproliferative Neoplasms (MPN)|Overview Page Link]])==


*[[HAEM5:Chronic myeloid leukaemia]]
*[[Chronic Myeloid Leukemia (CML), BCR-ABL1 Positive]]
*[[HAEM5:Chronic neutrophilic leukaemia]]
*[[Chronic Neutrophilic Leukemia (CNL)]]
*[[HAEM5:Polycythaemia vera]]
*[[Polycythemia Vera (PV)]]
*[[HAEM5:Primary myelofibrosis]]
*[[Primary Myelofibrosis (PMF)]]
*[[HAEM5:Essential thrombocythaemia]]
*[[Essential Thrombocythemia (ET)]]
*[[HAEM5:Chronic eosinophilic leukaemia]]
*[[Chronic Eosinophilic Leukemia, Not Otherwise Specified]]
*[[HAEM5:Myeloproliferative neoplasm, NOS]]
*[[Myeloproliferative Neoplasm (MPN), Unclassifiable]]


==Mastocytosis ([[HAEM4:Mastocytosis|Overview Page Link]])==
==Mastocytosis ([[Mastocytosis|Overview Page Link]])==


*[[HAEM5:Cutaneous mastocytosis]]
*[[Cutaneous Mastocytosis]]
*[[HAEM5:Systemic mastocytosis]]
*[[Systemic Mastocytosis]]
*[[HAEM5:Mast cell sarcoma]]
*[[Mast Cell Sarcoma]]


==Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB or FGFR1, or with PCM1-JAK2 ([[HAEM4:Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB or FGFR1, or with PCM1-JAK2|Overview Page Link]])==
==Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB or FGFR1, or with PCM1-JAK2 ([[Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB or FGFR1, or with PCM1-JAK2|Overview Page Link]])==


*[[HAEM5:Myeloid/lymphoid neoplasm with PDGFRA rearrangement]]
*[[Myeloid/Lymphoid Neoplasms with PDGFRA Rearrangement]]
*[[HAEM5:Myeloid/lymphoid neoplasm with PDGFRB rearrangement]]
*[[Myeloid/Lymphoid Neoplasms with PDGFRB Rearrangement]]
*[[HAEM5:Myeloid/lymphoid neoplasm with FGFR1 rearrangement]]
*[[Myeloid/Lymphoid Neoplasms with FGFR1 Rearrangement]]
*[[HAEM5:Myeloid/lymphoid neoplasm with JAK2 rearrangement]]
*[[Myeloid/Lymphoid Neoplasms with PCM1-JAK2]]


==Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) ([[HAEM4:Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN)|Overview Page Link]])==
==Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) ([[Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN)|Overview Page Link]])==


*[[HAEM5:Chronic myelomonocytic leukaemia]]
*[[Chronic Myelomonocytic Leukemia (CMML)]]
*[[HAEM5:Myelodysplastic/myeloproliferative neoplasm with neutrophilia]]
*[[Atypical Chronic Myeloid Leukemia (aCML), BCR-ABL1 Negative]]
*[[HAEM5:Juvenile myelomonocytic leukaemia]]
*[[Juvenile Myelomonocytic Leukemia (JMML)]]
*[[HAEM5:Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis|MDS/MPN with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T)]]
*[[Myelodysplastic/Myeloproliferative Neoplasms with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T)|MDS/MPN with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T)]]
*[[HAEM4:Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN), Unclassifiable|MDS/MPN, Unclassifiable]]
*[[Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN), Unclassifiable|MDS/MPN, Unclassifiable]]


==Myelodysplastic Syndromes (MDS) ([[HAEM4:Myelodysplastic Syndromes (MDS)|Overview Page Link]])==
==Myelodysplastic Syndromes (MDS) ([[Myelodysplastic Syndromes (MDS)|Overview Page Link]])==


*[[HAEM4:Myelodysplastic Syndrome (MDS) with Single Lineage Dysplasia|MDS with Single Lineage Dysplasia]]
*[[Myelodysplastic Syndrome (MDS) with Single Lineage Dysplasia|MDS with Single Lineage Dysplasia]]
*[[HAEM4:Myelodysplastic Syndrome with Ring Sideroblasts (MDS-RS)|MDS with Ring Sideroblasts (MDS-RS)]]
*[[Myelodysplastic Syndrome with Ring Sideroblasts (MDS-RS)|MDS with Ring Sideroblasts (MDS-RS)]]
*[[HAEM4:Myelodysplastic Syndrome with Ring Sideroblasts and Multilineage Dysplasia|MDS with Ring Sideroblasts and Multilineage Dysplasia]]
*[[Myelodysplastic Syndrome with Ring Sideroblasts and Multilineage Dysplasia|MDS with Ring Sideroblasts and Multilineage Dysplasia]]
*[[HAEM4:Myelodysplastic Syndrome (MDS) with Multilineage Dysplasia|MDS with Multilineage Dysplasia]]
*[[Myelodysplastic Syndrome (MDS) with Multilineage Dysplasia|MDS with Multilineage Dysplasia]]
*[[HAEM5:Myelodysplastic neoplasm with increased blasts|MDS with Excess Blasts]]
*[[Myelodysplastic Syndrome (MDS) with Excess Blasts|MDS with Excess Blasts]]
*[[HAEM5:Myelodysplastic neoplasm with low blasts and 5q deletion|MDS with Isolated del(5q)]]
*[[Myelodysplastic Syndrome (MDS) with Isolated del(5q)|MSD with Isolated del(5q)]]
*[[HAEM4:Myelodysplastic Syndrome (MDS), Unclassifiable|MDS, Unclassifiable]]
*[[Myelodysplastic Syndrome (MDS), Unclassifiable|MDS, Unclassifiable]]
*[[HAEM4:Refractory Cytopenia of Childhood]]
*[[Refractory Cytopenia of Childhood]]


==Myeloid Neoplasms with Germline Predisposition ([[HAEM4:Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Overview Page Link]])==
==Myeloid Neoplasms with Germline Predisposition ([[Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Overview Page Link]])==


*[[HAEM4:Acute Myeloid Leukaemia with Germline CEBPA Mutation]]
*[[Acute Myeloid Leukaemia with Germline CEBPA Mutation]]
*[[HAEM4:Myeloid Neoplasms with Germline DDX41 Mutation]]
*[[Myeloid Neoplasms with Germline DDX41 Mutation]]
*[[HAEM4:Myeloid Neoplasms with Germline RUNX1 Mutation]]
*[[Myeloid Neoplasms with Germline RUNX1 Mutation]]
*[[HAEM4:Myeloid Neoplasms with Germline ANKRD26 Mutation]]
*[[Myeloid Neoplasms with Germline ANKRD26 Mutation]]
*[[HAEM4:Myeloid Neoplasms with Germline ETV6 Mutation]]
*[[Myeloid Neoplasms with Germline ETV6 Mutation]]
*[[HAEM4:Myeloid Neoplasms with Germline GATA2 Mutation]]
*[[Myeloid Neoplasms with Germline GATA2 Mutation]]


==Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms ([[HAEM4:Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Overview Page Link]])==
==Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms ([[Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Overview Page Link]])==


*[[HAEM4:Acute Myeloid Leukemia (AML) with Recurrent Genetic Abnormalities|AML with Recurrent Genetic Abnormalities]]
*[[Acute Myeloid Leukemia (AML) with Recurrent Genetic Abnormalities|AML with Recurrent Genetic Abnormalities]]


   - [[HAEM5:Acute myeloid leukaemia with RUNX1::RUNX1T1 fusion|AML with t(8;21)(q22;q22.1); RUNX1-RUNX1T1]]
   - [[Acute Myeloid Leukemia (AML) with t(8;21)(q22;q22.1); RUNX1-RUNX1T1|AML with t(8;21)(q22;q22.1); RUNX1-RUNX1T1]]
   - [[HAEM5:Acute myeloid leukaemia with CBFB::MYH11 fusion|AML with with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11]]
   - [[Acute Myeloid Leukemia (AML) with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11|AML with with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11]]
   - [[HAEM5:Acute promyelocytic leukaemia with PML::RARA fusion]]
   - [[Acute Promyelocytic Leukemia (APL) with PML-RARA]]
   - [[HAEM5:Acute myeloid leukaemia with KMT2A rearrangement|AML with t(9;11)(p21.3;q23.3); KMT2A-MLLT3]]
   - [[Acute Myeloid Leukemia (AML) with t(9;11)(p21.3;q23.3); KMT2A-MLLT3|AML with t(9;11)(p21.3;q23.3); KMT2A-MLLT3]]
   - [[HAEM5:Acute myeloid leukaemia with DEK::NUP214 fusion|AML with t(6;9)(p23;q34.1); DEK-NUP214]]
   - [[Acute Myeloid Leukemia (AML) with t(6;9)(p23;q34.1); DEK-NUP214|AML with t(6;9)(p23;q34.1); DEK-NUP214]]
   - [[HAEM5:Acute myeloid leukaemia with MECOM rearrangement|AML with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2);GATA2, MECOM]]
   - [[Acute Myeloid Leukemia (AML) with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2);GATA2, MECOM|AML with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2);GATA2, MECOM]]
   - [[HAEM5:Acute myeloid leukaemia with RBM15::MRTFA fusion|AML Megakaryoblastic with t(1;22)(p13.3;q13.1);RBM15-MKL1]]
   - [[Acute Myeloid Leukemia (AML) Megakaryoblastic with t(1;22)(p13.3;q13.1);RBM15-MKL1|AML Megakaryoblastic with t(1;22)(p13.3;q13.1);RBM15-MKL1]]
   - [[HAEM5:Acute myeloid leukaemia with BCR::ABL1 fusion|AML with BCR-ABL1]]
   - [[Acute Myeloid Leukemia (AML) with BCR-ABL1|AML with BCR-ABL1]]
   - [[HAEM5:Acute myeloid leukaemia with NPM1 mutation|AML with Mutated NPM1]]
   - [[Acute Myeloid Leukemia (AML) with Mutated NPM1|AML with Mutated NPM1]]
   - [[HAEM5:Acute myeloid leukaemia with CEBPA mutation|AML with Biallelic Mutations of CEBPA]]
   - [[Acute Myeloid Leukemia (AML) with Biallelic Mutations of CEBPA|AML with Biallelic Mutations of CEBPA]]
   - [[HAEM4:Acute Myeloid Leukemia (AML) with Mutated RUNX1|AML with Mutated RUNX1]]
   - [[Acute Myeloid Leukemia (AML) with Mutated RUNX1|AML with Mutated RUNX1]]


*[[HAEM5:Acute myeloid leukaemia, myelodysplasia-related|AML with Myelodysplasia-Related Changes]]
*[[Acute Myeloid Leukemia (AML) with Myelodysplasia-Related Changes|AML with Myelodysplasia-Related Changes]]


*[[HAEM5:Myeloid neoplasm post cytotoxic therapy]]
*[[Therapy-Related Myeloid Neoplasms]]


*[[HAEM4:Acute Myeloid Leukemia (AML), Not Otherwise Specified|AML, Not Otherwise Specified]]
*[[Acute Myeloid Leukemia (AML), Not Otherwise Specified|AML, Not Otherwise Specified]]


   - [[HAEM5:Acute myeloid leukaemia with minimal differentiation|AML with Minimal Differentiation]]
   - [[Acute Myeloid Leukemia (AML) with Minimal Differentiation|AML with Minimal Differentiation]]
   - [[HAEM5:Acute myeloid leukaemia without maturation|AML without Maturation]]
   - [[Acute Myeloid Leukemia (AML) without Maturation|AML without Maturation]]
   - [[HAEM5:Acute myeloid leukaemia with maturation|AML with Maturation]]
   - [[Acute Myeloid Leukemia (AML) with Maturation|AML with Maturation]]
   - [[HAEM5:Acute myelomonocytic leukaemia]]
   - [[Acute Myelomonocytic Leukemia]]
   - [[HAEM5:Acute monocytic leukaemia]]
   - [[Acute Monoblastic and Monocytic Leukemia]]
   - [[HAEM5:Acute erythroid leukaemia]]
   - [[Pure Erythroid Leukemia]]
   - [[HAEM5:Acute megakaryoblastic leukaemia]]
   - [[Acute Megakaryoblastic Leukemia (AMKL)]]
   - [[HAEM5:Acute basophilic leukaemia]]
   - [[Acute Basophilic Leukemia]]
   - [[HAEM4:Acute Panmyelosis with Myelofibrosis]]
   - [[Acute Panmyelosis with Myelofibrosis]]


*[[HAEM5:Myeloid sarcoma]]
*[[Myeloid Sarcoma]]


*[[HAEM4:Myeloid Proliferations Associated with Down Syndrome]]
*[[Myeloid Proliferations Associated with Down Syndrome]]


   - [[HAEM5:Myeloid proliferations associated with Down syndrome]]
   - [[Transient Abnormal Myelopoiesis (TAM) Associated with Down Syndrome]]
   - [[HAEM5:Myeloid proliferations associated with Down syndrome]]
   - [[Myeloid Leukemia Associated with Down Syndrome]]


==Blastic Plasmacytoid Dendritic Cell Neoplasm ([[HAEM4:Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Overview Page Link]])==
==Blastic Plasmacytoid Dendritic Cell Neoplasm ([[Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Overview Page Link]])==


*[[HAEM5:Blastic plasmacytoid dendritic cell neoplasm]]
*[[Blastic Plasmacytoid Dendritic Cell Neoplasm]]


==Acute Leukemias of Ambiguous Lineage (MPAL) ([[HAEM4:Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Overview Page Link]])==
==Acute Leukemias of Ambiguous Lineage (MPAL) ([[Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Overview Page Link]])==


*[[HAEM4:Acute Leukemias of Ambiguous Lineage]]
*[[Acute Leukemias of Ambiguous Lineage]]


   - [[HAEM5:Acute undifferentiated leukaemia]]
   - [[Acute Undifferentiated Leukemia]]
   - [[HAEM5:Mixed-phenotype acute leukaemia with BCR::ABL1 fusion]]
   - [[Mixed Phenotype Acute Leukemia (MPAL) with t(9;22)(q34.1;q11.2); BCR-ABL1]]
   - [[HAEM5:Mixed-phenotype acute leukaemia with KMT2A rearrangement]]
   - [[Mixed Phenotype Acute Leukemia (MPAL) with t(v;11q23.3); KMT2A Rearranged]]
   - [[HAEM5:Mixed-phenotype acute leukaemia, B/myeloid]]
   - [[Mixed Phenotype Acute Leukemia (MPAL), B/Myeloid, Not Otherwise Specified]]
   - [[HAEM5:Mixed-phenotype acute leukaemia, T/myeloid]]
   - [[Mixed Phenotype Acute Leukemia (MPAL), T/Myeloid, Not Otherwise Specified]]
   - [[HAEM5:Mixed-phenotype acute leukaemia, rare types]]
   - [[Mixed-Phenotype Acute Leukemia, Not Otherwise Specified (NOS), Rare Types]]
   - [[HAEM4:Acute Leukemias of Ambiguous Lineage, Not Otherwise Specified (NOS)]]
   - [[Acute Leukemias of Ambiguous Lineage, Not Otherwise Specified (NOS)]]


==Precursor Lymphoid Neoplasms (B-ALL, T-ALL) ([[HAEM4:Precursor Lymphoid Neoplasms|Overview Page Link]])==
==Precursor Lymphoid Neoplasms (B-ALL, T-ALL) ([[Precursor Lymphoid Neoplasms|Overview Page Link]])==


*[[HAEM4:B-Lymphoblastic Leukemia/Lymphoma with Recurrent Genetic Abnormalities|B-Lymphoblastic Leukemia/Lymphoma (B-ALL) with Recurrent Genetic Abnormalities]]
*[[B-Lymphoblastic Leukemia/Lymphoma with Recurrent Genetic Abnormalities|B-Lymphoblastic Leukemia/Lymphoma (B-ALL) with Recurrent Genetic Abnormalities]]


   - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with BCR::ABL1 fusion|B-ALL with t(9;22)(q34.1;q11.2); BCR-ABL1]]
   - [[B-Lymphoblastic Leukemia/Lymphoma with t(9;22)(q34.1;q11.2); BCR-ABL1|B-ALL with t(9;22)(q34.1;q11.2); BCR-ABL1]]
   - [[HAEM5:B lymphoblastic leukaemia/lymphoma with KMT2A rearrangement|B-ALL with t(v;11q23.3); KMT2A-Rearranged]]
   - [[B-Lymphoblastic Leukemia/Lymphoma with t(v;11q23.3); KMT2A-Rearranged|B-ALL with t(v;11q23.3); KMT2A-Rearranged]]
   - [[HAEM5:B lymphoblastic leukaemia/lymphoma with ETV6::RUNX1 fusion|B-ALL with t(12;21)(p13.2;q22.1); ETV6-RUNX1]]
   - [[B-Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1|B-ALL with t(12;21)(p13.2;q22.1); ETV6-RUNX1]]
   - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with high hyperdiploidy|B-ALL with Hyperdiploidy]]
   - [[B-Lymphoblastic Leukemia/Lymphoma with Hyperdiploidy|B-ALL with Hyperdiploidy]]
   - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with hypodiploidy|B-ALL with Hypodiploidy]]
   - [[B-Lymphoblastic Leukemia/Lymphoma with Hypodiploidy|B-ALL with Hypodiploidy]]
   - [[HAEM5:B lymphoblastic leukaemia/lymphoma with IGH::IL3 fusion|B-ALL with t(5;14)(q31.1;q32.1); IGH/IL3]]
   - [[B-Lymphoblastic Leukemia/Lymphoma with t(5;14)(q31.1;q32.1); IGH/IL3|B-ALL with t(5;14)(q31.1;q32.1); IGH/IL3]]
   - [[HAEM5:B lymphoblastic leukaemia/lymphoma with TCF3::PBX1 fusion|B-ALL with t(1;19)(q23;p13.3); TCF3-PBX1]]
   - [[B-Lymphoblastic Leukemia/Lymphoma with t(1;19)(q23;p13.3); TCF3-PBX1|B-ALL with t(1;19)(q23;p13.3); TCF3-PBX1]]
   - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with BCR::ABL1-like features|B-ALL, BCR-ABL1-Like]]
   - [[B-Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like|B-ALL, BCR-ABL1-Like]]
   - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with iAMP21|B-ALL with iAMP21]]
   - [[B-Lymphoblastic Leukemia/Lymphoma with iAMP21|B-ALL with iAMP21]]
   - [[HAEM5:B-lymphoblastic leukaemia/lymphoma|B-ALL, Not Otherwise Specified]]
   - [[B-Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified|B-ALL, Not Otherwise Specified]]


*[[HAEM4:T-Lymphoblastic Leukemia/Lymphoma|T-Lymphoblastic Leukemia/Lymphoma (T-ALL)]]
*[[T-Lymphoblastic Leukemia/Lymphoma|T-Lymphoblastic Leukemia/Lymphoma (T-ALL)]]


   - [[HAEM5:Early T-precursor lymphoblastic leukaemia / lymphoma]]
   - [[Early T-Cell Precursor Lymphoblastic Leukemia]]
   - [[HAEM4:NK-Lymphoblastic Leukemia/Lymphoma]]
   - [[NK-Lymphoblastic Leukemia/Lymphoma]]


==Mature B-Cell Neoplasms (CLL, Plasma Cell Neoplasms, Non-Hodgkin B-cell Lymphomas) ([[HAEM4:Mature B-Cell Neoplasms|Overview Page Link]])==
==Mature B-Cell Neoplasms (CLL, Plasma Cell Neoplasms, Non-Hodgkin B-cell Lymphomas) ([[Mature B-Cell Neoplasms|Overview Page Link]])==


*[[HAEM5:Chronic lymphocytic leukaemia/small lymphocytic lymphoma]]
*[[Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma]]


   - [[HAEM5:Monoclonal B-cell lymphocytosis]]
   - [[Monoclonal B-cell Lymphocytosis]]


*[[HAEM4:B-cell Prolymphocytic Leukemia]]
*[[B-cell Prolymphocytic Leukemia]]


*[[HAEM5:Splenic marginal zone lymphoma]]
*[[Splenic Marginal Zone Lymphoma]]


*[[HAEM5:Hairy cell leukaemia]]
*[[Hairy Cell Leukemia]]


*[[HAEM4:Splenic B-cell Lymphoma/Leukemia, Unclassifiable]]
*[[Splenic B-cell Lymphoma/Leukemia, Unclassifiable]]


   - [[HAEM5:Splenic diffuse red pulp small B-cell lymphoma]]
   - [[Splenic Diffuse Red Pulp Small B-cell Lymphoma]]
   - [[HAEM5:Hairy cell leukaemia Variant]]
   - [[Hairy Cell Leukemia Variant]]


*[[HAEM5:Lymphoplasmacytic lymphoma]]
*[[Lymphoplasmacytic Lymphoma]]


   - [[HAEM5:Lymphoplasmacytic lymphoma]]
   - [[Waldenstrom Macroglobulinemia]]


*[[HAEM5:IgM monoclonal gammopathy of undetermined significance]]
*[[IgM Monoclonal Gammopathy of Undetermined Significance]]


*[[HAEM4:Heavy Chain Diseases]]
*[[Heavy Chain Diseases]]


   - [[HAEM5:Mu heavy chain disease]]
   - [[Mu Heavy Chain Disease]]
   - [[HAEM5:Gamma heavy chain disease]]
   - [[Gamma Heavy Chain Disease]]
   - [[HAEM5:Alpha heavy chain disease]]
   - [[Alpha Heavy Chain Disease]]


*[[HAEM4:Plasma Cell Neoplasms]]
*[[Plasma Cell Neoplasms]]


   - [[HAEM5:Non-IgM monoclonal gammopathy of undetermined significance]]
   - [[Non-IgM Monoclonal Gammopathy of Undetermined Significance]]
   - [[HAEM5:Plasma cell myeloma / multiple myeloma]]
   - [[Plasma Cell Myeloma]]
   - [[HAEM5:Plasma cell myeloma / multiple myeloma Variants]]
   - [[Plasma Cell Myeloma Variants]]
   - [[HAEM5:Plasmacytoma]]
   - [[Plasmacytoma]]
   - [[HAEM4:Monoclonal Immunoglobulin Deposition Diseases]]
   - [[Monoclonal Immunoglobulin Deposition Diseases]]
         - [[HAEM5:Immunoglobulin-related (AL) amyloidosis]]
         - [[Primary Amyloidosis]]
         - [[HAEM5:Monoclonal immunoglobulin deposition disease]]
         - [[Light Chain and Heavy Chain Deposition Disease]]
   - [[HAEM4:Plasma Cell Neoplasms with Associated Paraneoplastic Syndrome]]
   - [[Plasma Cell Neoplasms with Associated Paraneoplastic Syndrome]]
         - [[HAEM5:Plasma cell neoplasms with associated paraneoplastic syndrome]]
         - [[POEMS Syndrome]]
         - [[HAEM5:Plasma cell neoplasms with associated paraneoplastic syndrome]]
         - [[TEMPI Syndrome]]


*[[HAEM5:Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue]]
*[[Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue (MALT Lymphoma)]]


*[[HAEM5:Nodal marginal zone lymphoma]]
*[[Nodal Marginal Zone Lymphoma]]


   - [[HAEM5:Paediatric nodal marginal zone lymphoma]]
   - [[Paediatric Nodal Marginal Zone Lymphoma]]


*[[HAEM5:Follicular lymphoma]]
*[[Follicular Lymphoma]]


   - [[HAEM5:Follicular lymphoma]]
   - [[Testicular Follicular Lymphoma]]
   - [[HAEM5:In situ follicular B-cell neoplasm]]
   - [[In Situ Follicular Neoplasia]]
   - [[HAEM5:Duodenal-type follicular lymphoma]]
   - [[Duodenal-Type Follicular Lymphoma]]


*[[HAEM5:Paediatric-type follicular lymphoma]]
*[[Paediatric-Type Follicular Lymphoma]]


*[[HAEM5:Large B-cell lymphoma with IRF4 rearrangement]]
*[[Large B-cell Lymphoma with IRF4 Rearrangement]]


*[[HAEM5:Primary cutaneous follicle centre lymphoma]]
*[[Primary Cutaneous Follicle Centre Lymphoma]]


*[[HAEM5:Mantle cell lymphoma]]
*[[Mantle Cell Lymphoma]]


   - [[HAEM5:Leukaemic non-nodal mantle cell lymphoma]]
   - [[Leukemic Non-Nodal Mantle Cell Lymphoma]]
   - [[HAEM5:In situ mantle cell neoplasm]]
   - [[In Situ Mantle Cell Neoplasia]]


*[[HAEM4:Diffuse Large B-cell Lymphoma, Not Otherwise Specified]]
*[[Diffuse Large B-cell Lymphoma, Not Otherwise Specified]]


*[[HAEM5:T-cell/histiocyte-rich large B-cell lymphoma]]
*[[T-cell/Histiocyte-Rich Large B-cell Lymphoma]]


*[[HAEM5:Primary large B-cell lymphoma of immune-privileged sites]]
*[[Primary Diffuse Large B-cell Lymphoma of the CNS]]


*[[HAEM5:Primary cutaneous diffuse large B-cell lymphoma, leg type]]
*[[Primary Cutaneous Diffuse Large B-cell Lymphoma, Leg Type]]


*[[HAEM5:EBV-positive diffuse large B-cell lymphoma]]
*[[EBV-Positive Diffuse Large B-cell Lymphoma, Not Otherwise Specified (NOS)]]


*[[HAEM5:EBV-positive mucocutaneous ulcer]]
*[[EBV-Positive Mucocutaneous Ulcer]]


*[[HAEM5:Diffuse large B-cell lymphoma associated with chronic inflammation]]
*[[Diffuse Large B-cell Lymphoma Associated with Chronic Inflammation]]


   - [[HAEM5:Fibrin-associated large B-cell lymphoma]]
   - [[Fibrin-Associated Diffuse Large B-cell Lymphoma]]


*[[HAEM5:Lymphomatoid granulomatosis]]
*[[Lymphomatoid Granulomatosis]]


*[[HAEM5:Primary mediastinal large B-cell lymphoma]]
*[[Primary Mediastinal (Thymic) Large B-cell Lymphoma]]


*[[HAEM5:Intravascular large B-cell lymphoma]]
*[[Intravascular Large B-cell Lymphoma]]


*[[HAEM5:ALK-positive large B-cell lymphoma]]
*[[ALK-Positive Large B-cell Lymphoma]]


*[[HAEM5:Plasmablastic lymphoma]]
*[[Plasmablastic Lymphoma]]


*[[HAEM5:Primary effusion lymphoma]]
*[[Primary Effusion Lymphoma]]


*[[HAEM4:HHV8-Associated Lymphoproliferative Disorders]]
*[[HHV8-Associated Lymphoproliferative Disorders]]


   - [[HAEM5:KSHV/HHV8-associated multicentric Castleman disease]]
   - [[Multicentric Castleman Disease]]
   - [[HAEM5:KSHV/HHV8-positive diffuse large B-cell lymphoma]]
   - [[HHV8-Positive Diffuse Large B-cell Lymphoma, Not Otherwise Specified (NOS)]]
   - [[HAEM5:KSHV/HHV8-positive germinotropic lymphoproliferative disorder]]
   - [[HHV8-Positive Germinotropic Lymphoproliferative Disorder]]


*[[HAEM5:Burkitt lymphoma]]
*[[Burkitt Lymphoma]]


*[[HAEM5:High grade B-cell lymphoma with 11q aberrations]]
*[[Burkitt-Like Lymphoma with 11q Aberration]]


*[[HAEM4:High-Grade B-cell Lymphoma]]
*[[High-Grade B-cell Lymphoma]]


   - [[HAEM4:High-Grade B-cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements]]
   - [[High-Grade B-cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements]]
   - [[HAEM4:High-Grade B-cell Lymphoma, Not Otherwise Specified (NOS)]]
   - [[High-Grade B-cell Lymphoma, Not Otherwise Specified (NOS)]]


*[[HAEM5:Mediastinal grey zone lymphoma]]
*[[B-cell Lymphoma, Unclassifiable, with Features Intermediate Between Diffuse Large B-cell Lymphoma and Classic Hodgkin Lymphoma]]


==Mature T- and NK-cell Neoplasms ([[HAEM4:Mature T- and NK-cell Neoplasms|Overview Page Link]])==
==Mature T- and NK-cell Neoplasms ([[Mature T- and NK-cell Neoplasms|Overview Page Link]])==


*[[HAEM5:T-prolymphocytic leukaemia]]
*[[T-cell Prolymphocytic Leukemia]]


*[[HAEM5:T-large granular lymphocytic leukaemia]]
*[[T-cell Large Granular Lymphocytic Leukemia]]


*[[HAEM5:NK-large granular lymphocytic leukaemia]]
*[[Chronic Lymphoproliferative Disorder of NK Cells]]


*[[HAEM5:Aggressive NK-cell leukaemia]]
*[[Aggressive NK-cell Leukemia]]


*[[HAEM4:EBV-Positive T-cell and NK-cell Lymphoproliferative Diseases of Childhood]]
*[[EBV-Positive T-cell and NK-cell Lymphoproliferative Diseases of Childhood]]


   - [[HAEM5:Systemic EBV-positive T-cell lymphoma of childhood]]
   - [[Systemic EBV-Positive T-cell Lymphoma of Childhood]]
   - [[HAEM5:Systemic chronic active EBV disease]]
   - [[Chronic Active EBV Infection of T- and NK-cell Type, Systemic Form]]
   - [[HAEM5:Hydroa vacciniforme lymphoproliferative disorder]]
   - [[Hydroa Vacciniforme-Like Lymphoproliferative Disorder]]
   - [[HAEM5:Severe mosquito bite allergy]]
   - [[Severe Mosquito Bite Allergy]]


*[[HAEM5:Adult T-cell leukaemia/lymphoma]]
*[[Adult T-cell Leukemia/Lymphoma]]


*[[HAEM5:Extranodal NK/T-cell lymphoma]]
*[[Extranodal NK/T-cell Lymphoma, Nasal Type]]


*[[HAEM4:Intestinal T-cell Lymphoma]]
*[[Intestinal T-cell Lymphoma]]


   - [[HAEM5:Enteropathy-associated T-cell lymphoma]]
   - [[Enteropathy-Associated T-cell Lymphoma]]
   - [[HAEM5:Monomorphic epitheliotropic intestinal T-cell lymphoma]]
   - [[Monomorphic Epitheliotropic Intestinal T-cell Lymphoma]]
   - [[HAEM4:Intestinal T-cell Lymphoma, Not Otherwise Specified (NOS)]]
   - [[Intestinal T-cell Lymphoma, Not Otherwise Specified (NOS)]]
   - [[HAEM5:Indolent T-cell lymphoma of the gastrointestinal tract]]
   - [[Indolent T-cell Lymphoproliferative Disorder of the Gastrointestinal Tract]]


*[[HAEM5:Hepatosplenic T-cell lymphoma]]
*[[Hepatosplenic T-cell Lymphoma]]


*[[HAEM5:Subcutaneous panniculitis-like T-cell lymphoma]]
*[[Subcutaneous Panniculitis-Like T-cell Lymphoma]]


*[[HAEM5:Mycosis fungoides]]
*[[Mycosis Fungoides]]


*[[HAEM5:Sezary syndrome]]
*[[Sézary Syndrome]]


*[[HAEM4:Primary Cutaneous CD30 Positive T-cell Lymphoproliferative Disorders]]
*[[Primary Cutaneous CD30 Positive T-cell Lymphoproliferative Disorders]]


   - [[HAEM5:Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Lymphomatoid papulosis]]
   - [[Lymphomatoid Papulosis]]
   - [[HAEM5:Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Primary cutaneous anaplastic large cell lymphoma]]
   - [[Primary Cutaneous Anaplastic Large Cell Lymphoma]]


*[[HAEM4:Primary Cutaneous Peripheral T-cell Lymphomas, Rare Subtypes]]
*[[Primary Cutaneous Peripheral T-cell Lymphomas, Rare Subtypes]]


   - [[HAEM5:Primary cutaneous gamma/delta T-cell lymphoma]]
   - [[Primary Cutaneous Gamma Delta T-cell Lymphoma]]
   - [[HAEM5:Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma]]
   - [[Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma]]
   - [[HAEM5:Primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder]]
   - [[Primary Cutaneous Acral CD8+ T-cell Lymphoma]]
   - [[HAEM5:Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder]]
   - [[Primary Cutaneous CD4+ Small/Medium T-cell Lymphoproliferative Disorder]]


*[[HAEM5:Peripheral T-cell lymphoma, NOS]]
*[[Peripheral T-cell Lymphoma, Not Otherwise Specified (NOS)]]


*[[HAEM4:Angioimmunoblastic T-cell Lymphoma and Other Nodal Lymphomas of T Follicular Helper Cell Origin]]
*[[Angioimmunoblastic T-cell Lymphoma and Other Nodal Lymphomas of T Follicular Helper Cell Origin]]


   - [[HAEM5:Nodal TFH cell lymphoma, angioimmunoblastic-type]]
   - [[Angioimmunoblastic T-cell Lymphoma]]
   - [[HAEM5:Nodal TFH cell lymphoma, follicular-type]]
   - [[Follicular T-cell Lymphoma]]
   - [[HAEM5:Nodal TFH cell lymphoma, NOS]]
   - [[Nodal Peripheral T-cell Lymphoma with T Follicular Helper Phenotype]]


*[[HAEM5:ALK-positive anaplastic large cell lymphoma]]
*[[Anaplastic Large Cell Lymphoma, ALK-Positive]]


*[[HAEM5:ALK-negative anaplastic large cell lymphoma]]
*[[Anaplastic Large Cell Lymphoma, ALK-Negative]]


*[[HAEM5:Breast implant-associated anaplastic large cell lymphoma]]
*[[Breast Implant-Associated Anaplastic Large Cell Lymphoma]]


==Hodgkin Lymphomas ([[HAEM4:Hodgkin Lymphomas|Overview Page Link]])==  
==Hodgkin Lymphomas ([[Hodgkin Lymphomas|Overview Page Link]])==  


*[[HAEM5:Nodular lymphocyte predominant Hodgkin lymphoma]]
*[[Nodular Lymphocyte Predominant Hodgkin Lymphoma]]


*[[HAEM4:Classic Hodgkin Lymphoma]]
*[[Classic Hodgkin Lymphoma]]


   - [[HAEM5:Classic Hodgkin lymphoma]]
   - [[Nodular Sclerosis Classic Hodgkin Lymphoma]]
   - [[HAEM5:Classic Hodgkin lymphoma]]
   - [[Lymphocyte-Rich Classic Hodgkin Lymphoma]]
   - [[HAEM5:Classic Hodgkin lymphoma]]
   - [[Mixed Cellularity Classic Hodgkin Lymphoma]]
   - [[HAEM5:Classic Hodgkin lymphoma]]
   - [[Lymphocyte-Depleted Classic Hodgkin Lymphoma]]


==Immunodeficiency-Associated Lymphoproliferative Disorders ([[HAEM4:Immunodeficiency-Associated Lymphoproliferative Disorders|Overview Page Link]])==  
==Immunodeficiency-Associated Lymphoproliferative Disorders ([[Immunodeficiency-Associated Lymphoproliferative Disorders|Overview Page Link]])==  


*[[HAEM4:Lymphomas Associated with HIV Infection]]
*[[Lymphomas Associated with HIV Infection]]


*[[HAEM4:Post-Transplant Lymphoproliferative Disorders]]
*[[Post-Transplant Lymphoproliferative Disorders]]


   - [[HAEM4:Non-Destructive Post-Transplant Lymphoproliferative Disorders]]
   - [[Non-Destructive Post-Transplant Lymphoproliferative Disorders]]
   - [[HAEM5:Polymorphic lymphoproliferative disorders arising in immune deficiency / dysregulation]]
   - [[Polymorphic Post-Transplant Lymphoproliferative Disorders]]
   - [[HAEM4:Monomorphic Post-Transplant Lymphoproliferative Disorders (B- and T/NK-cell Types)]]
   - [[Monomorphic Post-Transplant Lymphoproliferative Disorders (B- and T/NK-cell Types)]]
         - [[HAEM4:Monomorphic B-cell PTLD]]
         - [[Monomorphic B-cell PTLD]]
         - [[HAEM4:Monomorphic T/NK-cell PTLD]]
         - [[Monomorphic T/NK-cell PTLD]]
   - [[HAEM4:Classical Hodgkin Lymphoma Post-Transplant Lymphoproliferative Disorder]]
   - [[Classical Hodgkin Lymphoma Post-Transplant Lymphoproliferative Disorder]]


*[[HAEM4:Other Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorders]]
*[[Other Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorders]]


==Histiocytic and Dendritic Cell Neoplasms ([[HAEM4:Histiocytic and Dendritic Cell Neoplasms|Overview Page Link]])==  
==Histiocytic and Dendritic Cell Neoplasms ([[Histiocytic and Dendritic Cell Neoplasms|Overview Page Link]])==  


*[[HAEM5:Histiocytic sarcoma]]
*[[Histiocytic Sarcoma]]


*[[HAEM4:Tumors Derived From Langerhans Cells]]
*[[Tumors Derived From Langerhans Cells]]


   - [[HAEM5:Langerhans cell histiocytosis]]
   - [[Langerhans Cell Histiocytosis]]
   - [[HAEM5:Langerhans cell sarcoma]]
   - [[Langerhans Cell Sarcoma]]


*[[HAEM5:Indeterminate dendritic cell tumour]]
*[[Indeterminate Dendritic Cell Tumour]]


*[[HAEM5:Interdigitating dendritic cell sarcoma]]
*[[Interdigitating Dendritic Cell Sarcoma]]


*[[HAEM5:Follicular dendritic cell sarcoma]]
*[[Follicular Dendritic Cell Sarcoma]]


   - [[HAEM5:EBV-positive inflammatory follicular dendritic cell sarcoma]]
   - [[Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcoma]]


*[[HAEM5:Fibroblastic reticular cell tumour]]
*[[Fibroblastic Reticular Cell Tumor]]


*[[HAEM5:Juvenile xanthogranuloma]]
*[[Disseminated Juvenile Xanthogranuloma]]


*[[HAEM5:Erdheim-Chester disease]]
*[[Erdheim-Chester Disease]]


==Notes==
==Notes==
<nowiki>*</nowiki>The hierarchical tumour classification structure displayed on this page is reproduced from the [https://tumourclassification.iarc.who.int/welcome/ WHO Classification of Tumours] with permission from the copyright holder, ©International Agency for Research on Cancer.
<nowiki>*</nowiki>The hierarchical tumour classification structure displayed on this page is reproduced from the [https://tumourclassification.iarc.who.int/welcome/ WHO Classification of Tumours] with permission from the copyright holder, ©International Agency for Research on Cancer.
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