HAEM4:Enteropathy-Associated T-cell Lymphoma: Difference between revisions
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==Cancer Category/Type== | ==Cancer Category/Type== | ||
*[[Mature T- and NK-cell Neoplasms]] | *[[HAEM4:Mature T- and NK-cell Neoplasms]] | ||
==Cancer Sub-Classification / Subtype== | ==Cancer Sub-Classification / Subtype== | ||
*[[Intestinal T-cell Lymphoma|Intestinal T-cell lymphoma]] | *[[HAEM4:Intestinal T-cell Lymphoma|Intestinal T-cell lymphoma]] | ||
==Definition / Description of Disease== | ==Definition / Description of Disease== | ||
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****Flow cytometry: sCD3<sup>_</sup>, CD8-, CD5- | ****Flow cytometry: sCD3<sup>_</sup>, CD8-, CD5- | ||
****IHC: | ****IHC: | ||
*****NKP46: significantly more positive in RCD2 IEL than normal IEL in CD and RCD1; not specific for RCD2 or EATL, can be seen in [[Monomorphic | *****NKP46: significantly more positive in RCD2 IEL than normal IEL in CD and RCD1; not specific for RCD2 or EATL, can be seen in [[HAEM5:Monomorphic epitheliotropic intestinal T-cell lymphoma|MEITL]]; not seen in [[HAEM5:Indolent T-cell lymphoma of the gastrointestinal tract|indolent T-cell LPD of GI tract]] | ||
*****CD30+ indicates progression to EATL | *****CD30+ indicates progression to EATL | ||
**** | **** | ||
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==Links== | ==Links== | ||
*[[Intestinal T-cell Lymphoma]]<nowiki/>s | *[[HAEM4:Intestinal T-cell Lymphoma]]<nowiki/>s | ||
*[[Monomorphic epitheliotropic intestinal T-cell lymphoma|Monomorphic epitheliotropi]]<nowiki/>[[Monomorphic epitheliotropic intestinal T-cell lymphoma|c intestinal T-cell lymphoma]] | *[[Monomorphic epitheliotropic intestinal T-cell lymphoma|Monomorphic epitheliotropi]]<nowiki/>[[Monomorphic epitheliotropic intestinal T-cell lymphoma|c intestinal T-cell lymphoma]] | ||