The Compendium of Cancer Genome Aberrations: Difference between revisions

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'''Welcome to the Compendium of Cancer Genome Aberrations (CCGA)! The CCGA is a collaborative effort to document and describe chromosome and other genomic abnormalities in cancer structured based on current WHO classification. The Wiki style interface allows for real-time editing and content sharing within our genetics community. This resource is supported by the [http://www.cancergenomics.org <u>Cancer Genomics Consortium (CGC)</u>] and others with an interest in clinical cytogenetics, molecular genetics and genomics in cancer.'''
'''Welcome to the CCGA!'''


*Join the CCGA community!  If you would like to contribute as an author, please complete a few brief questions on our '''[https://mms.cancergenomics.org/members/form.php?orgcode=CGC&fid=3830649 <u>Volunteer Form</u>]'''.
*An open resource focused on describing clinically relevant chromosomal and genomic abnormalities in cancer​
*Intended as a companion resource to the [https://tumourclassification.iarc.who.int/welcome/ WHO Classification of Tumours (WCT)] book series​
*Provides clinically significant genetic information for entities based on the current WCT disease ontology​
*Supported by the [https://www.cancergenomics.org/ Cancer Genomics Consortium (CGC)] and in collaboration with [https://whobluebooks.iarc.fr/about/ IARC] (publisher of the WCT book series)​
*Crowdsourced using a wiki-style interface, allowing for real-time editing and content sharing ​
*Contributed to by colleagues with an interest in clinical cytogenetics, molecular genetics and genomics in cancer ([https://mms.cancergenomics.org/members/form.php?orgcode=CGC&fid=3830649 Volunteer Form])


*'''[Mailto:CCGA@cancergenomics.org|Contact <u>Contact us</u>]''' for more information or suggestions for updates.
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*Meet our editorial '''<u>[[Leadership]]</u>'''.
 
*For contributors, we've created a '''<u>[[Video_Tutorial|Video Tutorial]]</u>''' demonstrating how to add content to the CCGA. Please also refer to helpful '''<u>[[Author Instructions|Author Instructions]]</u>'''.
 
{{Box-round|title=Newest Items|titlebackground=#06B5AD|Explore the great content available in '''<u>[[Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Acute Myeloid Leukemia (AML)]]</u>''', '''<u>[[Myelodysplastic Syndromes (MDS)|Myelodysplastic Syndromes (MDS)]]</u>''', '''<u>[[Myeloproliferative Neoplasms (MPN)|Myeloproliferative Neoplasms (MPN)]]</u>''', and '''<u>[[Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN)|Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN)]]</u>'''.
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[[File:Generic book cover heme and lymphoid.jpg|thumb|link=Acute_Myeloid_Leukemia_(AML)_and_Related_Precursor_Neoplasms|Coming Soon...Search content structured based on the WHO Classification ('''click book image'''). ''Reference: World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, Revised 4th edition. IARC Press: Lyon, France, 2017.'']]
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{{Box-round|titleforeground=white|titlebackground=#003399|title=Search Content Structured Based on the WHO Classification of Tumours (click book images below)|view-link=MediaWiki|content= Reference: [WHO Classification of Tumours.|Reference: [https://tumourclassification.iarc.who.int/welcome/ WHO Classification of Tumours.] The hierarchical tumour classification structure is reproduced with permission from the copyright holder, [https://whobluebooks.iarc.fr/about/ ©International Agency for Research on Cancer.]}}<div style="
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[[File:Inv 16 pathology.png |100px|link=:Category:Diseases]] '''Diseases''' '''[[:Category:Diseases A|A]]'''
| '''[[:Category:Diseases B|B]]''' | '''[[:Category:Diseases C|C]]''' | '''[[:Category:Diseases D|D]]''' | '''[[:Category:Diseases E|E]]''' | '''[[:Category:Diseases F|F]]'''
| '''[[:Category:Diseases G|G]]''' | '''[[:Category:Diseases H|H]]''' | '''[[:Category:Diseases I|I]]''' | '''[[:Category:Diseases J|J]]''' | '''[[:Category:Diseases K|K]]''' | '''[[:Category:Diseases L|L]]''' | '''[[:Category:Diseases M|M]]''' | '''[[:Category:Diseases N|N]]''' | '''[[:Category:Diseases O|O]]''' | '''[[:Category:Diseases P|P]]''' | '''[[:Category:Diseases Q|Q]]''' | '''[[:Category:Diseases R|R]]''' | '''[[:Category:Diseases S|S]]''' | '''[[:Category:Diseases T|T]]''' | '''[[:Category:Diseases U|U]]'''
| '''[[:Category:Diseases V|V]]''' | '''[[:Category:Diseases W|W]]''' | '''[[:Category:Diseases X|X]]''' | '''[[:Category:Diseases Y|Y]]''' | '''[[:Category:Diseases Z|Z]]'''


 
[[File:CGC logo only.png|100px|link=Main_Page]]<span id="fp-span-cgc-pre"> '''CGC Workgroups Recurrent Loci Tables'''</span><span id="fp-span-cgc" style="display: block; margin-top: -62px; margin-left: 385px;"> [[AML Table: Recurrent Genomic Alterations Detected by Chromosomal Microarray|AML]] | [[MDS, MDS/MPN and MPN Tables: Recurrent Genomic Alterations Detected by Chromosomal Microarray|MDS/MPN]] | [[CLL Tables: Regions of Recurrent Copy Number Change and CN-LOH|CLL]] | [[Recurrent Genomic Alterations in Pediatric and Adult Central Nervous System Tumors Detected by Chromosomal Microarray|CNS Tumors]] | [[Plasma Cell Neoplasms Tables: Recurrent Cytogenomic Alterations|Plasma Cell Neoplasms]] | [[Breast Cancer: Recurrent Genomic Alterations|Breast Cancer]] | [[Renal Cell Neoplasia Tables: Recurrent Cytogenomic Alterations|Renal Neoplasia]] | [[B-ALL Tables: Prognostic Genomic Abnormalities and Recurrent Gene Fusions|B-ALL]]</span>
[[File:Example_translocation.png|100px|link=:Category:Structural Abnormalities]] '''Structural Abnormalities''' '''[[:Category:Structural Abnormalities Chromosome 1|1]]'''
| '''[[:Category:Structural Abnormalities Chromosome 2|2]]''' | '''[[:Category:Structural Abnormalities Chromosome 3|3]]''' | '''[[:Category:Structural Abnormalities Chromosome 4|4]]'''
| '''[[:Category:Structural Abnormalities Chromosome 5|5]]''' | '''[[:Category:Structural Abnormalities Chromosome 6|6]]'''
| '''[[:Category:Structural Abnormalities Chromosome 7|7]]''' | '''[[:Category:Structural Abnormalities Chromosome 8|8]]''' | '''[[:Category:Structural Abnormalities Chromosome 9|9]]'''
| '''[[:Category:Structural Abnormalities Chromosome 10|10]]''' | '''[[:Category:Structural Abnormalities Chromosome 11|11]]''' | '''[[:Category:Structural Abnormalities Chromosome 12|12]]'''
| '''[[:Category:Structural Abnormalities Chromosome 13|13]]''' | '''[[:Category:Structural Abnormalities Chromosome 14|14]]''' | '''[[:Category:Structural Abnormalities Chromosome 15|15]]'''
| '''[[:Category:Structural Abnormalities Chromosome 16|16]]''' | '''[[:Category:Structural Abnormalities Chromosome 17|17]]''' | '''[[:Category:Structural Abnormalities Chromosome 18|18]]'''
| '''[[:Category:Structural Abnormalities Chromosome 19|19]]''' | '''[[:Category:Structural Abnormalities Chromosome 20|20]]''' | '''[[:Category:Structural Abnormalities Chromosome 21|21]]'''
| '''[[:Category:Structural Abnormalities Chromosome 22|22]]''' | '''[[:Category:Structural Abnormalities Chromosome X|X]]''' | '''[[:Category:Structural Abnormalities Chromosome Y|Y]]'''
 
 
[[File:Fish_zoomed.png|100px|link=:Category:Cancer Genes]] '''Cancer Genes''' '''[[:Category:Cancer Genes A|A]]'''
| '''[[:Category:Cancer Genes B|B]]''' | '''[[:Category:Cancer Genes C|C]]''' | '''[[:Category:Cancer Genes D|D]]''' | '''[[:Category:Cancer Genes E|E]]''' | '''[[:Category:Cancer Genes F|F]]'''
| '''[[:Category:Cancer Genes G|G]]''' | '''[[:Category:Cancer Genes H|H]]''' | '''[[:Category:Cancer Genes I|I]]''' | '''[[:Category:Cancer Genes J|J]]''' | '''[[:Category:Cancer Genes K|K]]''' | '''[[:Category:Cancer Genes L|L]]''' | '''[[:Category:Cancer Genes M|M]]''' | '''[[:Category:Cancer Genes N|N]]''' | '''[[:Category:Cancer Genes O|O]]''' | '''[[:Category:Cancer Genes P|P]]''' | '''[[:Category:Cancer Genes Q|Q]]''' | '''[[:Category:Cancer Genes R|R]]''' | '''[[:Category:Cancer Genes S|S]]''' | '''[[:Category:Cancer Genes T|T]]''' | '''[[:Category:Cancer Genes U|U]]'''
| '''[[:Category:Cancer Genes V|V]]''' | '''[[:Category:Cancer Genes W|W]]''' | '''[[:Category:Cancer Genes X|X]]''' | '''[[:Category:Cancer Genes Y|Y]]''' | '''[[:Category:Cancer Genes Z|Z]]'''
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[[File:Circos.png|100px|link=Main_Page]] '''Cancer Genomes''' [[Hematologic and Lymphoid]] | [[Solid Tumors]] | [[CNS]] | [[Pediatric]]
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[[File:Logo-black.png.twimg.2560.png|30px|link=https://twitter.com/ccgawiki]]
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<h4>[[Submit an Article]]</h4>
<h4>Author Resources</h4>
[[Video Tutorial]]
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[[Acute Myeloid Leukemia (AML) with t(8;21)(q22;q22.1); RUNX1-RUNX1T1|Example Article]]


[[:Category:Recently Added Pages|Recently Added Pages]]
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[[Technical Standards and Protocols]]


[[Analysis Pipelines]]
- [https://mms.cancergenomics.org/members/form.php?orgcode=CGC&fid=3830649 Volunteer Form]
 
[[Educational Materials]]


- [[Description_of_CCGA_Roles|Role Descriptions]]
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[[Request Membership]]
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Latest revision as of 14:10, 21 July 2025

Welcome to the CCGA!

  • An open resource focused on describing clinically relevant chromosomal and genomic abnormalities in cancer​
  • Intended as a companion resource to the WHO Classification of Tumours (WCT) book series​
  • Provides clinically significant genetic information for entities based on the current WCT disease ontology​
  • Supported by the Cancer Genomics Consortium (CGC) and in collaboration with IARC (publisher of the WCT book series)​
  • Crowdsourced using a wiki-style interface, allowing for real-time editing and content sharing ​
  • Contributed to by colleagues with an interest in clinical cytogenetics, molecular genetics and genomics in cancer (Volunteer Form)


 


editSearch Content Structured Based on the WHO Classification of Tumours (click book images below)
Reference: WHO Classification of Tumours. The hierarchical tumour classification structure is reproduced with permission from the copyright holder, ©International Agency for Research on Cancer.


CGC Workgroups Recurrent Loci Tables AML | MDS/MPN | CLL | CNS Tumors | Plasma Cell Neoplasms | Breast Cancer | Renal Neoplasia | B-ALL


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