Recurrent Genomic Alterations in Pediatric and Adult Central Nervous System Tumors Detected by Chromosomal Microarray: Difference between revisions
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| Anaplastic PXA, WHO grade III / Ganglioglioma, WHO Grade III | | Anaplastic PXA, WHO grade III / Ganglioglioma, WHO Grade III | ||
| '''Loss:''' monosomy 9 / 9p deletion, but no diagnostic findings | | '''Loss:''' monosomy 9 / 9p deletion, but no diagnostic findings | ||
| '''Mutation:''' BRAF V600E less common here than in PXA, grade II | | '''Mutation:''' BRAF V600E less common here than in PXA, grade II<br> | ||
'''Loss:''' CDKN2A/CDKN2B | '''Loss:''' CDKN2A/CDKN2B | ||
| CDKN2A/CDKN2B loss may correlate with anaplastic histology | | CDKN2A/CDKN2B loss may correlate with anaplastic histology | ||
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|Glioblastoma, WHO grade IV | |Glioblastoma, WHO grade IV | ||
|IDH-mutant | |IDH-mutant | ||
|'''Gain:''' 1q, 2q, 3q, 7, 16p, 17q, 21q | |'''Gain:''' 1q, 2q, 3q, 7, 16p, 17q, 21q<br> | ||
'''Loss:''' 6q, 8q, 9p, 9q, 10q, 13q, 17p, 22q | '''Loss:''' 6q, 8q, 9p, 9q, 10q, 13q, 17p, 22q | ||
''' Chromothripsis:''' observed | ''' Chromothripsis:''' observed | ||