Recurrent Genomic Alterations in Pediatric and Adult Central Nervous System Tumors Detected by Chromosomal Microarray: Difference between revisions
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| PMID:26829751; PMID:23633565; PMID:26778052 PMID:23583981 | | PMID:26829751; PMID:23633565; PMID:26778052 PMID:23583981 | ||
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| Ganglioglioma | |||
| Only 30% are abnormal by karyotype '''Gain:''' polysomy 7 | |||
| '''Mutations:''' BRAF V600E in 20-60% of cases (can be concurrent with CDKN2A homozygous deletion); '''Fusions:''' KIAA1549-BRAF | |||
| Generally indolent tumors for which surgical resection can be curative | |||
| PMID:25461780; PMID:23583981; PMID:11996800 PMID:23609006; PMID:29880043 | |||
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