|
|
| Line 87: |
Line 87: |
| !Notes | | !Notes |
| |- | | |- |
| |<span class="blue-text">EXAMPLE:</span> | | | |
| 7
| | | |
| |<span class="blue-text">EXAMPLE:</span> Loss | | | |
| |<span class="blue-text">EXAMPLE:</span> | | | |
| chr7:1-159,335,973 [hg38]
| | | |
| |<span class="blue-text">EXAMPLE:</span> | | | |
| chr7
| | | |
| |<span class="blue-text">EXAMPLE:</span> Yes | | | |
| |<span class="blue-text">EXAMPLE:</span> Yes | |
| |<span class="blue-text">EXAMPLE:</span> No | |
| |<span class="blue-text">EXAMPLE:</span> | |
| Presence of monosomy 7 (or 7q deletion) is sufficient for a diagnosis of AML with MDS-related changes when there is ≥20% blasts and no prior therapy (add reference). Monosomy 7/7q deletion is associated with a poor prognosis in AML (add reference).
| |
| |- | | |- |
| |<span class="blue-text">EXAMPLE:</span> | | | |
| 8
| | | |
| |<span class="blue-text">EXAMPLE:</span> Gain | | | |
| |<span class="blue-text">EXAMPLE:</span> | | | |
| chr8:1-145,138,636 [hg38]
| | | |
| |<span class="blue-text">EXAMPLE:</span> | | | |
| chr8
| | | |
| |<span class="blue-text">EXAMPLE:</span> No | | | |
| |<span class="blue-text">EXAMPLE:</span> No | |
| |<span class="blue-text">EXAMPLE:</span> No | |
| |<span class="blue-text">EXAMPLE:</span> | |
| Common recurrent secondary finding for t(8;21) (add reference).
| |
| |} | | |} |
| ==Characteristic Chromosomal Patterns== | | ==Characteristic Chromosomal Patterns== |
|
| |
|
| |
|
| Not Applicable | | Not Applicable |
| Line 125: |
Line 116: |
| !Notes | | !Notes |
| |- | | |- |
| |<span class="blue-text">EXAMPLE:</span> | | | |
| Co-deletion of 1p and 18q
| | | |
| |<span class="blue-text">EXAMPLE:</span> Yes | | | |
| |<span class="blue-text">EXAMPLE:</span> No | | | |
| |<span class="blue-text">EXAMPLE:</span> No | | | |
| |<span class="blue-text">EXAMPLE:</span> | |
| See chromosomal rearrangements table as this pattern is due to an unbalanced derivative translocation associated with oligodendroglioma (add reference).
| |
| |} | | |} |
| ==Gene Mutations (SNV / INDEL)== | | ==Gene Mutations (SNV / INDEL)== |
