Compendium of Cancer Genome Aberrations

HAEM5:ALK-positive anaplastic large cell lymphoma: Difference between revisions

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|ALK
|ALK<ref name=":24" /><ref name=":7" /><ref name=":8" /><ref name=":9" /><ref name=":25" /><ref name=":26" /><ref name=":23" />
|Therapeutic Resistance mutations
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|No
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|No
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|Yes
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*ALK kinase domain secondary mutations, including L1196 M, G1269A, L1152R, C1156Y, I1171T, F1174 L, G1202R, and S1206Y, have been identified as the key mechanism of resistance
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*ALK kinase domain secondary mutations, including L1196 M, G1269A, L1152R, C1156Y, I1171T, F1174 L, G1202R, and S1206Y, have been identified as the key mechanism of resistance<ref name=":23" /><ref name=":24" /><ref name=":7" /><ref name=":8" /><ref name=":9" /><ref name=":25" /><ref name=":26" />
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