HAEM5:Acute myeloid leukaemia with RBM15::MRTFA fusion: Difference between revisions
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|''RBM15'' and ''MKL1'' | |''RBM15'' and ''MKL1'' | ||
|''RBM15''(''OTT'')::''MKL1''(''MAL'')||The majority of both genes retained in the fusion 5’ ''DEK'' and 3’''NUP214''(''CAN'') with the pathogenic derivative being | |''RBM15''(''OTT'')::''MKL1''(''MAL'')||The majority of both genes are retained in the fusion, specifically 5’ ''DEK'' and 3’''NUP214''(''CAN''), with the pathogenic derivative being the der(22).||t(1;22)(p13.3;q13.1) | ||
|Rare (AML) | |Rare (AML) | ||
|D | |D | ||
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==Gene Mutations (SNV/INDEL)== | ==Gene Mutations (SNV/INDEL)== | ||
* COSMIC does not have specific information on mutations related to this subtype of AML. | *COSMIC does not have specific information on mutations related to this subtype of AML. | ||
{| class="wikitable sortable" | {| class="wikitable sortable" | ||