CNS5:Diffuse midline glioma, H3 K27-altered: Difference between revisions

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Linda Cooley, MD, MBA, Children's Mercy Hospital
Linda Cooley, MD, MBA, Children's Mercy Hospital
==WHO Classification of Disease==
==WHO Classification of Disease==


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==Definition / Description of Disease==
==Related Terminology==
 
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==Synonyms / Terminology==
 
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==Epidemiology / Prevalence==
 
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==Clinical Features==
 
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{| class="wikitable"
|'''Signs and Symptoms'''
|EXAMPLE Asymptomatic (incidental finding on complete blood counts)
 
EXAMPLE B-symptoms (weight loss, fever, night sweats)
 
EXAMPLE Fatigue
 
EXAMPLE Lymphadenopathy (uncommon)
|-
|'''Laboratory Findings'''
|EXAMPLE Cytopenias
 
EXAMPLE Lymphocytosis (low level)
|}
 
==Sites of Involvement==
 
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==Morphologic Features==
 
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==Immunophenotype==
 
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{| class="wikitable sortable"
|-
!Finding!!Marker
|-
|Positive (universal)||EXAMPLE CD1
|-
|Positive (subset)||EXAMPLE CD2
|-
|Negative (universal)||EXAMPLE CD3
|-
|Negative (subset)||EXAMPLE CD4
|}


==Gene Rearrangements==
==Gene Rearrangements==