Breast Cancer: Recurrent Genomic Alterations: Difference between revisions
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|''ZNF703'' | |''ZNF703'' | ||
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|Gain of function | |Gain of function | ||
|[https://omim.org/entry/617045 617045] | |[https://omim.org/entry/617045 617045] | ||
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|amplification | |amplification | ||
|Diseases: ER positive BC and luminal B; Therapy: BC cell lines overexpressing ZNF703 may be more resistant to tamoxifen treatment; Prognosis: may be poor in some cases (part of 8p11.2 gain/amplification) | |Diseases: ER positive BC and luminal B; Therapy: BC cell lines overexpressing ZNF703 may be more resistant to tamoxifen treatment; Prognosis: may be poor in some cases (part of 8p11.2 gain/amplification) | ||
|[https://pubmed.ncbi.nlm.nih.gov/21328542/ 21328542]; [https://pubmed.ncbi.nlm.nih.gov/21337521/ 21337521]; [https://pubmed.ncbi.nlm.nih.gov/23991038/ 23991038]; [https://pubmed.ncbi.nlm.nih.gov/24156016/ 24156016] | |[https://pubmed.ncbi.nlm.nih.gov/21328542/ 21328542]; [https://pubmed.ncbi.nlm.nih.gov/21337521/ 21337521]; [https://pubmed.ncbi.nlm.nih.gov/23991038/ 23991038]; [https://pubmed.ncbi.nlm.nih.gov/24156016/ 24156016]; [https://pubmed.ncbi.nlm.nih.gov/33389351/ 33389351] | ||
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Abbreviations: BC, breast cancer. TNBC, triple negative breast cancer. | Abbreviations: BC, breast cancer. TNBC, triple negative breast cancer. | ||