CNS5:Pleomorphic xanthoastrocytoma: Difference between revisions
| [unchecked revision] | [unchecked revision] |
| Line 117: | Line 117: | ||
|NF2, others | |NF2, others | ||
|D | |D | ||
|No (not guideline-specific, recurrent in PXA) | |No (not guideline-specific, recurrent in PXA) | ||
|Frequently reported, may occur with other losses | |Frequently reported, may occur with other losses | ||
|- | |- | ||
| Line 123: | Line 123: | ||
|Loss | |Loss | ||
|chr 8p (varied region) | |chr 8p (varied region) | ||
|Varies | |Varies | ||
|P | |P | ||
|No | |No | ||
|Seen in a subset, less common ((PMID: 28181325) | |Seen in a subset, less common ((PMID: 28181325) | ||
|- | |||
|LOH | |||
|Copy-neutral | |||
|Varies (mainly 9p21) | |||
|CDKN2A, CDKN2B | |||
|D, P | |||
|Yes (NCCN) | |||
|copy-neutral LOH; supports diagnosis | |||
|} | |} | ||
==Characteristic Chromosomal or Other Global Mutational Patterns== | ==Characteristic Chromosomal or Other Global Mutational Patterns== | ||