HAEM5:B-lymphoblastic leukaemia/lymphoma with hypodiploidy: Difference between revisions
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|Constitutive activation of mitogenic and anti-apoptotic pathways, driving uncontrolled cell proliferation, survival, and malignant transformation. | |Constitutive activation of mitogenic and anti-apoptotic pathways, driving uncontrolled cell proliferation, survival, and malignant transformation. | ||
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|''CDKN2A/B, TP53, RB1''; Loss of function mutations | |''CDKN2A/B, TP53, RB1''; Loss of function mutations<ref name=":2" /> | ||
|Cell cycle and apoptosis | |Cell cycle and apoptosis | ||
|Propagation of genetically altered cells. | |Propagation of genetically altered cells. | ||