HAEM5:EBV-positive diffuse large B-cell lymphoma: Difference between revisions

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!Gene; Genetic Alteration!!Pathway!!Pathophysiologic Outcome
!Gene; Genetic Alteration!!Pathway!!Pathophysiologic Outcome
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|''SOCS1;'' Activating mutations
|''SOCS1;'' Activating mutations<ref name=":1" />
|JAK-STAT and interferon gamma (INFγ) signaling pathways
|JAK-STAT and interferon gamma (INFγ) signaling pathways
|Negative regulator of the JAK-STAT INFγ signaling pathways<ref name=":1" /><ref name=":7" />
|Negative regulator of the JAK-STAT INFγ signaling pathways<ref name=":1" /><ref name=":7" />
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|<span class="blue-text">EXAMPLE:</span> ''CDKN2A''; Inactivating mutations
|''STAT3 and STAT6''; Activating mutations<ref name=":1" />
|<span class="blue-text">EXAMPLE:</span> Cell cycle regulation
|<span class="blue-text">EXAMPLE:</span> Cell cycle regulation
|<span class="blue-text">EXAMPLE:</span> Unregulated cell division
|<span class="blue-text">EXAMPLE:</span> Unregulated cell division