Compendium of Cancer Genome Aberrations

Plasma Cell Neoplasms Tables: Recurrent Cytogenomic Alterations: Difference between revisions

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|6q16.3
|6q16.3
|Loss
|Loss
|''COQR, GRIK2''
|''[[COQR]], [[GRIK2]]''
|Recurrent
|Recurrent
|3
|3
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|8q24.3
|8q24.3
|Gain
|Gain
|''MAPK15, TOP1MT, CYP11B11 (P450), ZNF41, 616, 707'' and ''ZNF517''
|''[[MAPK15]], [[TOP1MT]], [[CYP11B11]] (P450), ZNF41, 616, 707'' and ''ZNF517''
|Recurrent
|Recurrent
|3
|3
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|9q34.3
|9q34.3
|Gain
|Gain
|''ZNF79, CDK9, SET''
|''[[ZNF79]], [[CDK9]], SET''
|Recurrent
|Recurrent
|3
|3
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|10q23.31
|10q23.31
|Loss
|Loss
|''PTEN''
|''[[PTEN]]''
|Recurrent
|Recurrent
|2
|2
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|11q13.1/q13.4
|11q13.1/q13.4
|Gain
|Gain
|''SCYL1, MAP3K11, CCND1, FGF4, FGF3, NUMA,'' and ''RELT''
|''[[SCYL1]], [[MAP3K11]], [[CCND1]], [[FGF4]], [[FGF3]], [[NUMA]],'' and ''[[RELT]]''
|Recurrent
|Recurrent
|3
|3
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|11q22.1-q22.3
|11q22.1-q22.3
|Homozygous Loss
|Homozygous Loss
|BIRC3, BIRC2, MMP cluster
|[[BIRC3]], [[BIRC2]], MMP cluster
|Recurrent
|Recurrent
|3
|3
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|12p13.1
|12p13.1
|Loss
|Loss
|''CDKN1B, APOLD1''
|''[[CDKN1B]], [[APOLD1]]''
|Recurrent
|Recurrent
|3
|3
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|13q14.11/q14.2
|13q14.11/q14.2
|Loss
|Loss
|''TNFSF11, RB1, P2RY5, RCBTB2''
|''[[TNFSF11]], [[RB1]], [[P2RY5]], [[RCBTB2]]''
|Poor prognostic marker
|Poor prognostic marker
|1
|1
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|13q32.2
|13q32.2
|Loss
|Loss
|''TGDS''
|''[[TGDS]]''
|Recurrent
|Recurrent
|2
|2
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|14q24.1-q24.3
|14q24.1-q24.3
|Loss
|Loss
|''MLH3''
|''[[MLH3]]''
|Recurrent
|Recurrent
|2
|2
Line 459: Line 459:
|14q32.32
|14q32.32
|Homozygous Loss
|Homozygous Loss
|''RCOR1, TRAF3, AMN, CDC42BPB''
|''[[RCOR1]], [[TRAF3]], [[AMN]], [[CDC42BPB]]''
|Recurrent
|Recurrent
|3
|3
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|15q24.1
|15q24.1
|Gain
|Gain
|''CYP11A1, ARID3B, CSK, etc.''
|''[[CYP11A1]], [[ARID3B]], [[CSK]], etc.''
|Recurrent
|Recurrent
|3
|3
Line 482: Line 482:
|16p11.2
|16p11.2
|Loss
|Loss
|''TP53TG3''
|''[[TP53TG3]]''
|Recurrent
|Recurrent
|3
|3
Line 496: Line 496:
|16q12.1-q12.2
|16q12.1-q12.2
|Homozygous Loss
|Homozygous Loss
|''CYLD, SALL1''
|''[[CYLD]], [[SALL1]]''
|Recurrent
|Recurrent
|3
|3
Line 503: Line 503:
|16q24.3
|16q24.3
|Loss
|Loss
|CBFA2T3 and others
|''[[CBFA2T3]]'' and others
|Recurrent
|Recurrent
|3
|3
Line 532: Line 532:
|17p13
|17p13
|Loss
|Loss
|''ATP1B2, '''TP53''', WRAP5, EFNB3''
|''[[ATP1B2]], '''[[TP53]]''', [[WRAP5]], [[EFNB3]]''
|Predictive & prognostic
|Predictive & prognostic
|1
|1
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|19p/ 19p13
|19p/ 19p13
|Gain
|Gain
|''ICAM4,ICAM4, IBCL2L12, TYK2, IL2,'' and ''DNMT1''
|''ICAM4,ICAM4, [[IBCL2L12]], [[TYK2]], [[IL2]],'' and ''[[DNMT1]]''
|Recurrent
|Recurrent
|3
|3
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|22q21
|22q21
|mostly Gain
|mostly Gain
|''PRAME''
|''[[PRAME]]''
|Recurrent, Associated with relapse
|Recurrent, Associated with relapse
|2
|2
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|Xp22.33
|Xp22.33
|Loss
|Loss
|''SHOX, CRLF2, IL3RA''
|''[[SHOX]], [[CRLF2]], [[IL3RA]]''
|Recurrent
|Recurrent
|3
|3
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|Xq21.31-q21.32
|Xq21.31-q21.32
|Loss
|Loss
|''PABPC5, PCDHX''
|''[[PABPC5]], [[PCDHX]]''
|Recurrent
|Recurrent
|3
|3
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|Xq27.3-q28
|Xq27.3-q28
|Gain
|Gain
|''AFF2, MTMR1, etc''
|''[[AFF2]], [[MTMR1]], etc''
|Recurrent
|Recurrent
|3
|3
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