Plasma Cell Neoplasms Tables: Recurrent Cytogenomic Alterations: Difference between revisions

[unchecked revision][unchecked revision]
Added Table 1 commentary
Adding gene links
Line 15: Line 15:
|t(4;14)
|t(4;14)
|Poor prognosis, predicts bortezomib response
|Poor prognosis, predicts bortezomib response
|''IGH''
|''[[IGH]]''
|-
|-
|t(6;14)
|t(6;14)
|Good prognosis
|Good prognosis
|''IGH''
|''[[IGH]]''
|-
|-
|t(14;16)
|t(14;16)
|Poor prognosis
|Poor prognosis
|''IGH''
|''[[IGH]]''
|-
|-
|t(11;14)
|t(11;14)
|Good prognosis
|Good prognosis
|''IGH''
|''[[IGH]]''
|-
|-
|t(14;20)
|t(14;20)
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|8q24.2+
|8q24.2+
|Recurrent
|Recurrent
|''MYC''
|''[[MYC]]''
|-
|-
|9p+
|9p+
Line 98: Line 98:
|del(10q23.31)
|del(10q23.31)
|Recurrent
|Recurrent
|''PTEN''
|''[[PTEN]]''
|-
|-
|11q+
|11q+
Line 110: Line 110:
|del(13q32.2)
|del(13q32.2)
|Recurrent
|Recurrent
|''TGDS''
|''[[TGDS]]''
|-
|-
|del(14q)
|del(14q)
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|22q21+
|22q21+
|Associated with relapse
|Associated with relapse
|''PRAME''
|''[[PRAME]]''
|-
|-
|del(X), X+, X CN-LOH
|del(X), X+, X CN-LOH
Line 690: Line 690:
| 17p13
| 17p13
|Loss
|Loss
|''[[ATP1B2]], '''[[TP53]]''', [[WRAP5]], [[EFNB3]]''
|''[[ATP1B2]], [[TP53]], [[WRAP5]], [[EFNB3]]''
| Predictive & prognostic
| Predictive & prognostic
|1
|1