Recurrent Genomic Alterations in Pediatric and Adult Central Nervous System Tumors Detected by Chromosomal Microarray: Difference between revisions
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|80% occur in children; associated with Li-Fraumeni syndrome; Lack of SMARCB1/SMARCA4 aberrations can be used to distinguish CPC from AT/RT | |80% occur in children; associated with Li-Fraumeni syndrome; Lack of SMARCB1/SMARCA4 aberrations can be used to distinguish CPC from AT/RT | ||
|PMID:24478045; PMID:21990040; PMID:25575132; PMID:18157090; PMID:25336695 | |PMID:24478045; PMID:21990040; PMID:25575132; PMID:18157090; PMID:25336695 | ||
'''Table 2:''' Adult CNS Tumors. Table derived from CGC CNS Workgroup 2015-2018. | |||
{| class="wikitable" | |||
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! ADULT TUMOR | |||
! SUBTYPES | |||
! BROAD ABERRATIONS (>10Mb) | |||
! FOCAL ABERRATIONS (<10Mb) | |||
! CLINICAL FEATURES | |||
! REFERENCES | |||
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|'''GLIOMAS''' | |||
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