Compendium of Cancer Genome Aberrations

HAEM5:ALK-positive anaplastic large cell lymphoma: Difference between revisions

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!Notes
!Notes
|-
|-
|LRP1B
|LRP1B<ref name=":4" />
|TSG
|TSG
|19%
|19%
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|
|-
|-
|TP53
|TP53<ref name=":4" />
|TSG
|TSG
|11%
|11%
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!Gene; Genetic Alteration!!Pathway!!Pathophysiologic Outcome
!Gene; Genetic Alteration!!Pathway!!Pathophysiologic Outcome
|-
|-
|EXAMPLE: BRAF and MAP2K1; Activating mutations
|ALK; fusion protein derivatives
|EXAMPLE: MAPK signaling
|Ras-ERK:  
|EXAMPLE: Increased cell growth and proliferation
|Increased cell growth and proliferation
|-
|-
|EXAMPLE: CDKN2A; Inactivating mutations
|EXAMPLE: CDKN2A; Inactivating mutations
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