Compendium of Cancer Genome Aberrations

HAEM5:Enteropathy-associated T-cell lymphoma: Difference between revisions

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!Gene; Genetic Alteration!!Pathway!!Pathophysiologic Outcome
!Gene; Genetic Alteration!!Pathway!!Pathophysiologic Outcome
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|EXAMPLE: BRAF and MAP2K1; Activating mutations
|SETD2, TET2, YLPM1; loss of function mutations
|EXAMPLE: MAPK signaling
|Gene regulation
|EXAMPLE: Increased cell growth and proliferation
|EXAMPLE: Increased cell growth and proliferation
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|EXAMPLE: CDKN2A; Inactivating mutations
|JAK1, JAK3, STAT3, STAT5B, SOCS1
|EXAMPLE: Cell cycle regulation
|JAK-STAT pathway
|EXAMPLE: Unregulated cell division
|EXAMPLE: Unregulated cell division
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