Gliomas, glioneuronal tumours, and neuronal tumours (Overview Page Link)
Gliomas, glioneuronal tumours, and neuronal tumours
Adult-type diffuse gliomas
- Astrocytoma, IDH-mutant
- Oligodendroglioma, IDH-mutant and 1p/19q-codeleted
- Glioblastoma, IDH-wildtype
Paediatric-type diffuse low-grade gliomas
- Diffuse astrocytoma, MYB- or MYBL1-altered
- Angiocentric glioma
- Polymorphous low-grade neuroepithelial tumour of the young
- Diffuse low-grade glioma, MAPK pathway-altered
Paediatric-type diffuse high-grade gliomas
- Diffuse midline glioma, H3 K27-altered
- Diffuse hemispheric glioma, H3 G34-mutant
- Diffuse paediatric-type high-grade glioma, H3-wildtype and IDH-wildtype
- Infant-type hemispheric glioma
Circumscribed astrocytic gliomas
- Pilocytic astrocytoma
- High-grade astrocytoma with piloid features
- Pleomorphic xanthoastrocytoma
- Subependymal giant cell astrocytoma
- Chordoid glioma
- Astroblastoma, MN1-altered
Glioneuronal and neuronal tumours
- Ganglioglioma
- Gangliocytoma
- Desmoplastic infantile ganglioglioma / desmoplastic infantile astrocytoma
- Dysembryoplastic neuroepithelial tumour
- Diffuse glioneuronal tumour with oligodendroglioma-like features and nuclear clusters
- Papillary glioneuronal tumour
- Rosette-forming glioneuronal tumour
- Myxoid glioneuronal tumour
- Diffuse leptomeningeal glioneuronal tumour
- Multinodular and vacuolating neuronal tumour
- Dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease)
- Central neurocytoma
- Extraventricular neurocytoma
- Cerebellar liponeurocytoma
Ependymal tumours
- Supratentorial ependymoma
- Supratentorial ependymoma, ZFTA fusion-positive
- Supratentorial ependymoma, YAP1 fusion-positive
- Posterior fossa ependymoma
- Posterior fossa group A (PFA) ependymoma
- Posterior fossa group B (PFB) ependymoma
- Spinal ependymoma
- Spinal ependymoma, MYCN-amplified
- Myxopapillary ependymoma
- Subependymoma
- Choroid plexus papilloma
- Atypical choroid plexus papilloma
- Choroid plexus carcinoma
Medulloblastoma
Medulloblastomas, molecularly defined
- Medulloblastoma, WNT-activated
- Medulloblastoma, SHH-activated and TP53-wildtype
- Medulloblastoma, SHH-activated and TP53-mutant
- Medulloblastoma, non-WNT/non-SHH
Medulloblastomas, histologically defined
- Medulloblastoma, histologically defined
Other CNS embryonal tumours
- Atypical teratoid/rhabdoid tumour
- Cribriform neuroepithelial tumour
- Embryonal tumour with multilayered rosettes
- CNS neuroblastoma, FOXR2-activated
- CNS tumour with BCOR internal tandem duplication
- CNS embryonal tumour NEC/NOS
- Pineocytoma
- Pineal parenchymal tumour of intermediate differentiation
- Pineoblastoma
- Papillary tumour of the pineal region
- Desmoplastic myxoid tumour of the pineal region, SMARCB1-mutant
Cranial and paraspinal nerve tumours (Overview Page Link)
- Schwannoma
- Neurofibroma
- Perineurioma
- Hybrid nerve sheath tumours
- Malignant melanotic nerve sheath tumour
- Malignant peripheral nerve sheath tumour
- Cauda equina neuroendocrine tumour (previously paraganglioma)
- Meningioma
Mesenchymal, non-meningothelial tumours involving the CNS (Overview Page Link)
Soft tissue tumours
Fibroblastic and myofibroblastic tumours
- Solitary fibrous tumour
Vascular tumours
- Haemangiomas and vascular malformations
- Haemangioblastoma
Skeletal muscle tumours
- Rhabdomyosarcoma
Tumours of uncertain differentiation
- Intracranial mesenchymal tumour, FET::CREB fusion-positive
- CIC-rearranged sarcoma
- Primary intracranial sarcoma, DICER1-mutant
- Ewing sarcoma
Chondro-osseous tumours
Chondrogenic tumours
- Mesenchymal chondrosarcoma
- Chondrosarcoma
Notochordal tumours
- Chordoma
Diffuse meningeal melanocytic neoplasms
- Diffuse meningeal melanocytic neoplasms: Melanocytosis and melanomatosis
Circumscribed meningeal melanocytic neoplasms
- Circumscribed meningeal melanocytic neoplasms: Melanocytoma and melanoma
Haematolymphoid tumours involving the CNS (Overview Page Link)
Lymphomas
CNS lymphomas
- Primary diffuse large B-cell lymphoma of the CNS
- Immunodeficiency-associated CNS lymphomas
- Lymphomatoid granulomatosis
- Intravascular large B-cell lymphoma
Miscellaneous rare lymphomas in the CNS
- MALT lymphoma of the dura
- Other low-grade B-cell lymphomas of the CNS
- Anaplastic large cell lymphoma (ALK+/ALK−)
- T-cell and NK/T-cell lymphomas
Histiocytic tumours
- Erdheim-Chester disease
- Rosai-Dorfman disease
- Juvenile xanthogranuloma
- Langerhans cell histiocytosis
- Histiocytic sarcoma
- Germ cell tumours of the CNS
- Adamantinomatous craniopharyngioma
- Papillary craniopharyngioma
- Pituicytoma, granular cell tumour of the sellar region, and spindle cell oncocytoma
- Pituitary adenoma / pituitary neuroendocrine tumour
- Pituitary blastoma
- Metastases to the brain and spinal cord parenchyma
- Metastases to the meninges
Genetic tumour syndromes involving the CNS (Overview Page Link)
- Neurofibromatosis type 1
- Neurofibromatosis type 2
- Schwannomatosis
- Von Hippel-Lindau syndrome
- Tuberous sclerosis
- Li-Fraumeni syndrome
- Cowden syndrome
- Constitutional mismatch repair deficiency syndrome
- Familial adenomatous polyposis 1
- Naevoid basal cell carcinoma syndrome
- Rhabdoid tumour predisposition syndrome
- Carney complex
- DICER1 syndrome
- Familial paraganglioma syndromes
- Melanoma-astrocytoma syndrome
- Familial retinoblastoma
- BAP1 tumour predisposition syndrome
- Fanconi anaemia
- ELP1-medulloblastoma syndrome